HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-(aminomethyl)-N-tert-butylbiphenyl-2-sulfonamide → 5-n-Butyl-4-[[2'-(N-t-butylsulfamoyl)biphenyl-4-yl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-(aminomethyl)-N-tert-butylbiphenyl-2-sulfonamide | HCID 10064489 | — |
| Reactant | Ethyl valerate carbethoxyhydrazone | HCID 53752329 | — |
| Product | 5-n-Butyl-4-[[2'-(N-t-butylsulfamoyl)biphenyl-4-yl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one | HCID 10388637 | 72% |
Reaction Steps
By the procedure of Example 9, Step C, [[2'-(N-t-butylsulfamoyl)biphenyl-4-yl)methyl]amine (from Step F) was reacted with ethyl valerimidate carbethoxyhydrazone (from Example 2, Step A) to give a 72% yield of the title compound as a white foam; satisfactory purity by TLC in 94:6 CH2Cl2 --MeOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05411980 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-de7cef4b573e4c35bd9196e081ad8395 |
| Source note | uspto-grants-1995_05 |