反应详情

温度

120 °C

2,6-dichloro-9-isopropylpurine (0.019 g, 0.081 mmol) was dissolved in butanol (0.5 ml) and aniline (0.044 ml, 0.244 mmol) was added. The reaction mixture was heated to 120° C. for 10 hr, cooled, diluted with EtOAc and washed 3 times with water. The mixture was dried over MgSO4 and concentrated to an off white solid.

1. temperaturecooled
2. washwashed 3 times with water
3. dry with materialThe mixture was dried over MgSO4
4. concentrationconcentrated to an off white solid