関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Aniline | HCID 6115 | — |
| 反応物 | 2,6-dichloro-9-(propan-2-yl)-9H-purine | HCID 11218490 | — |
| 溶媒 | 1-Butanol | HCID 263 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 2-Chloro-6-anilino-9-isopropylpurine | HCID 21951839 | — |
反応手順
2,6-dichloro-9-isopropylpurine (0.019 g, 0.081 mmol) was dissolved in butanol (0.5 ml) and aniline (0.044 ml, 0.244 mmol) was added. The reaction mixture was heated to 120° C. for 10 hr, cooled, diluted with EtOAc and washed 3 times with water. The mixture was dried over MgSO4 and concentrated to an off white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05866702 |
|---|
| 出典データセット | uspto-grants-1999_02 |
|---|
| ORD ID | ord-943d2e0a209749b3bce63c83c715e21b |
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| 出典メモ | uspto-grants-1999_02 |
|---|
