反应详情

N-Benzyloxycarbonyl-L-tert-leucine-N-2-(2-methoxy-ethoxymethoxy)ethylamide was deprotected by hydrogenolysis, as described in Step G. Reaction was complete after 3 hours, leaving a single ninhydrin positive spot on TLC (5% methanol in dichloromethane). The solvent wwas removed to give the title compound as a white foam. Yield: 1.17 9(92%). 1H--NMR; δCD3OD), 4.66 (2H, s), 3.68-3.48 (7H, br m), 3.40 (1H, m), 3.35 (3H, s) and 0.95 (9H, s).

1. customReaction