Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | Pyridine, 3,3′-(1Z)-1,2-ethenediylbis[2-fluoro-, (Z)- | HCID 22942261 | — |
| Product | HCID 470618 | HCID 470618 | 54.9% |
Reaction Steps
A mixture of Z-1,2-di-(2-fluoropyridinyl)ethylene (0.436 g) and cyclopropylamine (2 g) was heated at 125° C. in a sealed tube for 12 hours. The mixture was cooled and fractionated directly over silica gel to give 11-cyclopropyl-dipyrido[2,3-b:3',2'-f]azepine (0.258 g), mp 184°-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05869482 |
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| Source dataset | uspto-grants-1999_02 |
|---|
| ORD ID | ord-610ebf02fa134b85954beeb6a44c9775 |
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| Source note | uspto-grants-1999_02 |
|---|
