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HRID36230

反应详情

EQUATION

反应方程式

HRID 36230 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：CCCCc1nn(C(C(=O)OC)C(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1
HCID178441941

未命名化合物

PRODUCTS

生成物

1
结构：CCCCc1nn(C(C(=O)O)C(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1
HCID178441942

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

结构：CO.ClCCl
溶剂HCID21226129

未命名化合物

PROCEDURE

实验过程

The hydrolysis of 5-n-butyl-2-[1-(carbomethoxy)isobutyl]-2,4-dihydro-4-[[2'-(5-tetrazolyl)biphenyl-4-yl]methyl]-3H-1,2,4-triazol-3-one (from Example 38) using methanolic sodium hydroxide in THF was carried out as described in Example 7. The material obtained after work-up (71%) was homogeneous by TLC in 10% MeOH/CH2Cl2, mass spectrum (FAB) m/e 475 (M+1)+.

WORKUP

后处理

  1. customThe material obtained after work-up (71%)