HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dimethylaniline → 4-[(6,11-Dihydro-5H-dibenz[b,e]azepin-5-yl) carbonyl]-N-(2,3-dimethylphenyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dimethylaniline | HCID 6893 | — |
| Reactant | 4-[(6,11-dihydro-5H-dibenz[b,e]azepin-5-yl)carbonyl]benzoyl chloride | HCID 53802244 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 4-[(6,11-Dihydro-5H-dibenz[b,e]azepin-5-yl) carbonyl]-N-(2,3-dimethylphenyl]benzamide | HCID 15307992 | 98.8% |
Reaction Steps
As described for Example 123, a mixture of 0.361 g of 4-[(6,11-dihydro-5H-dibenz[b,e]azepin-5-yl)carbonyl]benzoyl chloride, 0.101 g of triethylamine and 0.145 g of 2,3-dimethylaniline is stirred for 1.5 hr. and worked up to give 0.44 g of crystals, m.p. 248°-251° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05869483 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-bbc48ec6b5bf4ee085444be7a34022ba |
| Source note | uspto-grants-1999_02 |