HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 14213080, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | (R)-1-Benzyl 4-tert-butyl 2-benzylsuccinate | HCID 14213077 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14213080 | HCID 14213080 | 62.8% |
Reaction Steps
8 ml of trifluoroacetic acid are added, at 0° C., to a solution of 2 g (5.6 mmol) of phenylmethyl 1,1-dimethylethyl 2-(phenylmethyl)-1,4-butanedioate in 16 ml of dichloromethane. After 7 h at room temperature, the mixture is evaporated to dryness and the residue is recrystallized from cyclohexane. 1.05 g of a white product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05869518 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-1e42076ff9874623ba395359a355d072 |
| Source note | uspto-grants-1999_02 |