Ammonia → HCID 54565766, compound

HRID 362656Notes

Reaction equation

HRID 362656 reaction equation
[F:1][CH:2]([F:19])[O:3][C:4]1[N:8]([CH3:9])[N:7]=[C:6]([N:10]2[C:14]([CH3:15])=[C:13]([C:16](Cl)=[O:17])[CH:12]=[N:11]2)[CH:5]=1.[NH3:20]>O1CCCC1>[F:1][CH:2]([F:19])[O:3][C:4]1[N:8]([CH3:9])[N:7]=[C:6]([N:10]2[C:14]([CH3:15])=[C:13]([C:16]([NH2:20])=[O:17])[CH:12]=[N:11]2)[CH:5]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 54055627HCID 54055627, compound

Product 1

HCID 54565766HCID 54565766, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

0.98 g (3.38 mmol) 1-(5-Difluoromethoxy-1-methyl-3-pyrazolyl)-5-methyl-4-pyrazolecarbonyl chloride was dissolved in 20 ml tetrahydrofuran and 50 ml aqueous ammonia (33%) was added with stirring. After stirring for 3 hours at room temperature, the mixture was concentrated to half and acidified with dilute hydrochloric acid. The precipitate was suction filtered off, washed with a small amount of water and dried.

Workup

  1. stirringAfter stirring for 3 hours at room temperature
  2. concentrationthe mixture was concentrated to half
  3. filtrationfiltered off
  4. washwashed with a small amount of water
  5. customdried

Sources & evidence

ORD record
ord-ab5b4dde538945b9896e7df58011de47
Source dataset
uspto-grants-1999_02
Patent number
US05869686

Reaction notes

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