Ethanol → HCID 53681002, compound

HRID 362659Notes

Reaction equation

HRID 362659 reaction equation
[F:1][CH:2]([F:12])[O:3][C:4]1[N:8]([CH3:9])[N:7]=[C:6]([NH:10][NH2:11])[CH:5]=1.CN([CH:16]=[CH:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])C.[CH2:23](O)[CH3:24]>>[F:12][CH:2]([F:1])[O:3][C:4]1[N:8]([CH3:9])[N:7]=[C:6]([N:10]2[C:23]([CH3:24])=[C:17]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH:16]=[N:11]2)[CH:5]=1

Participants

4

Reactant 3

HCID 702Ethanol2×HCID 121015Ethyl 3-(N,N-dimethylamino)acrylateHCID 15767488HCID 15767488, compound

Product 1

HCID 53681002HCID 53681002, compound

Procedure

3.0 g (16.8 mmol) 5-Difluoromethoxy-3-hydrazino-1-methylpyrazole was added to 25 ml ethanol and treated dropwise with 2.96 g (16.0 mmol) ethyl dimethylaminomethylenacetate dissolved in 25 ml ethanol. The mixture was heated under reflux for 2 hours. After cooling the precipitate was suction filtered off.

Workup

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 2 hours
  3. temperatureAfter cooling the precipitate
  4. filtrationfiltered off

Sources & evidence

ORD record
ord-131cafd5c1404bbc8956fde2adc37278
Source dataset
uspto-grants-1999_02
Patent number
US05869686

Reaction notes

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