Hydrochloric Acid → HCID 54561485, compound

Participants

Reaction Steps

A mixture of cyclopropyl (4-amino-3-nitrophenyl)methanone (80 g), prepared as described in U.S. Pat. No. 3,657,267, and concentrated HCl (420 ml) was stirred and refluxed for 30 minutes. The reaction mixture was cooled and water was added. The precipitate was filtered off, washed with water and dried, yielding 80 g (84.5%) of 1-(4-amino-3-nitrophenyl)-4-chloro-1-butanone; mp. 150° C. (intermediate 10).

Provenance & Evidence