HRID362935

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8110

Butyl isocyanate

C5H9NO

结构：Nc1ccc(O)cc1C(=O)NCC1CCN(C(c2ccccc2)c2ccccc2)CC1

HCID67596187

未命名化合物

PRODUCTS

生成物

结构：CCCCNC(=O)Nc1ccc(OC(=O)NCCCC)cc1C(=O)NCC1CCN(C(c2ccccc2)c2ccccc2)CC1

HCID67595156

未命名化合物

PROCEDURE

实验过程

{2-amino-5-hydroxy-N-[(1-diphenylmethylpiperidin-4-yl)methyl]-benzamide and n-butyliso-cyanate}: mp 197°-199° C.; 1H NMR(CDCl3)ppm: 0.90 (3H, t), 1.20-1.90 (11H, m), 2.88 (2H, m), 3.18 (2H, td), 3.25 (2H, dd), 4.23 (1H, s), 5.31 (1H, bs), 6.88 (1H, dd), 6.97 (1H, d), 7.10-741 (11H, m), 7.95 (1H, d), 8.66 (1H, s), 9.40 (1H, s); and,

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f40694478ab941fcbafe1e7ed21f908a
来源数据集: uspto-grants-1999_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05872115
来源说明: uspto-grants-1999_02

反应 SMILES

[NH2:1][C:2]1[CH:30]=[CH:29][C:28]([OH:31])=[CH:27][C:3]=1[C:4]([NH:6][CH2:7][CH:8]1[CH2:13][CH2:12][N:11]([CH:14]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:10][CH2:9]1)=[O:5].[CH2:32]([N:36]=[C:37]=[O:38])[CH2:33][CH2:34][CH3:35]>>[CH2:32]([NH:36][C:37]([O:31][C:28]1[CH:29]=[CH:30][C:2]([NH:1][C:4]([NH:6][CH2:7][CH2:8][CH2:9][CH3:10])=[O:5])=[C:3]([CH:27]=1)[C:4]([NH:6][CH2:7][CH:8]1[CH2:9][CH2:10][N:11]([CH:14]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH2:12][CH2:13]1)=[O:5])=[O:38])[CH2:33][CH2:34][CH3:35]