Butyl isocyanate → 5-n-butylcarbamyloxy-2-(N'-n-butylureido)-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide

Participants

Role	Name	HCID	Charge
Reactant	Butyl isocyanate	HCID 8110	—
Reactant	2-amino-5-hydroxy-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide	HCID 67596187	—
Product	5-n-butylcarbamyloxy-2-(N'-n-butylureido)-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide	HCID 67595156	—

Reaction Steps

{2-amino-5-hydroxy-N-[(1-diphenylmethylpiperidin-4-yl)methyl]-benzamide and n-butyliso-cyanate}: mp 197°-199° C.; 1H NMR(CDCl3)ppm: 0.90 (3H, t), 1.20-1.90 (11H, m), 2.88 (2H, m), 3.18 (2H, td), 3.25 (2H, dd), 4.23 (1H, s), 5.31 (1H, bs), 6.88 (1H, dd), 6.97 (1H, d), 7.10-741 (11H, m), 7.95 (1H, d), 8.66 (1H, s), 9.40 (1H, s); and,

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05872115
Source dataset	uspto-grants-1999_02
ORD ID	ord-f40694478ab941fcbafe1e7ed21f908a
Source note	uspto-grants-1999_02