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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 362985Generated: October 30, 2026

Acetic Anhydride → 1-acetoxy-2-[2-(N,N-dimethylamino)ethoxy]-1-(1-naphthyl)ethane

https://huagongshe.com/reaction/362985

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
ReactantTriethylamineHCID 8471—
Reactant2-[2-(N,N-dimethylamino)ethoxy]-1-(1-naphthyl)ethanol hydrochlorideHCID 67598018—
SolventPyridineHCID 1049—
Product1-acetoxy-2-[2-(N,N-dimethylamino)ethoxy]-1-(1-naphthyl)ethaneHCID 54033212—

Reaction Steps

2-[2-(N,N-dimethylamino)ethoxy]-1-(1-naphthyl)ethanol hydrochloride was reacted with acetic anhydride in pyridine in the presence of triethylamine to obtain oily 1-acetoxy-2-[2-(N,N-dimethylamino)ethoxy]-1-(1-naphthyl)ethane (compound No. 300).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05872117
Source datasetuspto-grants-1999_02
ORD IDord-b932ab0ea8544f42b11f4e87335e8a9e
Source noteuspto-grants-1999_02