反应详情

To a solution of 4-(1,3-diphenyl-1-propoxy)benzyl bromide 6-6 (0.381 g, 1.0 mmol) in acetonitrile (7 ml) was added 4-aminopyridine (6-7) (94 mg, 1.0 mmol) with stirring at room temperature. The mixture was stirred for 3 hrs and the resulting white suspension was filtered. The white solid obtained 6-8, melted at 215°-216.5° C. Recrystallization from acetonitrile raised the melting point to 218.5°-220° C.

1. stirringThe mixture was stirred for 3 hrs
2. filtrationthe resulting white suspension was filtered
3. customThe white solid obtained 6-8, melted at 215°-216.5° C
4. customRecrystallization from acetonitrile
5. temperatureraised the melting point to 218.5°-220° C.