4-Aminopyridine → HCID 70052096, compound

HRID 363022Notes

Reaction equation

HRID 363022 reaction equation
[CH:1]1([CH:7]([CH:17]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)[O:8][C:9]2[CH:16]=[CH:15][C:12]([CH2:13][Br:14])=[CH:11][CH:10]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:23][C:24]1[CH:29]=[CH:28][N:27]=[CH:26][CH:25]=1>C(#N)C>[Br-:14].[NH2:23][C:24]1[CH:29]=[CH:28][N+:27]([CH2:13][C:12]2[CH:15]=[CH:16][C:9]([O:8][CH:7]([CH:17]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]3)[CH:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)=[CH:10][CH:11]=2)=[CH:26][CH:25]=1

Participants

4

Reactant 2

HCID 17274-AminopyridineHCID 53788509HCID 53788509, compound

Product 1

HCID 70052096HCID 70052096, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

8-5 (183 mg, 0.5 mmol) and 4-aminopyridine 8-6 (47 mg, 0.5 mmol) were reacted in acetonitrile (4 ml) as in Example 1. Recovered white solid 8-7. mp: 248°-249° C.

Workup

  1. customRecovered white solid 8-7

Sources & evidence

ORD record
ord-c1617869bf7d4ea09c09ef18b2db4f61
Source dataset
uspto-grants-1999_02
Patent number
US05872138

Reaction notes

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