Methylamine → HCID 178458307, compound

Participants

Reaction Steps

A solution of ethyl 6-hydroxy-2-(2-propoxyphenyl)pyrimidine-4-carboxylate (0.40 g) and methylamine in industrial methylated spirit (33%, 15 ml) in ethanol (15 ml) was stirred at ambient temperature for 6 hours and then allowed to stand for 3 days. The reaction mixture was evaporated under reduced pressure to yield a crude product which was recrystallized from ethanol to yield the title compound, 0.26 g, m.p. 165°-6° C.

Provenance & Evidence