alpha-(4-Methoxycarbonylbenzyloxy)styrene → alpha-[4-(Hydroxymethyl)benzyloxy]styrene

HRID 363539Notes

Reaction equation

HRID 363539 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].C[O:8][C:9]([C:11]1[CH:26]=[CH:25][C:14]([CH2:15][O:16][C:17]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH2:18])=[CH:13][CH:12]=1)=O>>[OH:8][CH2:9][C:11]1[CH:26]=[CH:25][C:14]([CH2:15][O:16][C:17]([C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH2:18])=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 15219435alpha-(4-Methoxycarbonylbenzyloxy)styreneHCID 21226445Aluminium lithium hydride

Product 1

HCID 21253606alpha-[4-(Hydroxymethyl)benzyloxy]styrene

Procedure

This compound was prepared by lithium aluminium hydride reduction of α-(4-methoxycarbonylbenzyloxy)styrene: 1H NMR (CCl4) δ 2.65 (1H, t, J 4.5 Hz), 4.15 (1H, d, J 3 Hz), 4.43 (2H, d, J 4.5 Hz), 4.60 (1H, d, J 3 Hz), 4.80 (2H, s), 7.1-7.7 (9H, m).

Sources & evidence

ORD record
ord-69887bf1f2cd47b497536a184270d04c
Source dataset
uspto-grants-1999_02
Patent number
US05874511

Reaction notes

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