HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 10398910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl Acrylate | HCID 7294 | — |
| Reactant | P-Anisidine | HCID 7732 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 10398910 | HCID 10398910 | 57.3% |
Reaction Steps
Following the general procedure of Example I, 339 mmols of methyl acrylate were reacted with 25 mmols of crude 4-methoxyaniline in 30 mL of acetonitrile and in the presence of 38 mmols of concentrated HCl and 2.5 mmols of cuprous oxide. The process resulted in a 57.3% yield of methyl 2-chloro-3-(4-methoxyphenyl)propionate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04604243 |
| Source dataset | uspto-grants-1986_08 |
| ORD ID | ord-e3aefe0f07134f7eb17a0fd4334d94d2 |
| Source note | uspto-grants-1986_08 |