7,8-Dimethoxy-3-[3-(methylamino)propyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → HCID 13579668, compound

HRID 364076Notes

Reaction equation

HRID 364076 reaction equation
[CH3:1][O:2][C:3]1[C:19]([O:20][CH3:21])=[CH:18][C:6]2[CH2:7][C:8](=[O:17])[N:9]([CH2:12][CH2:13][CH2:14][NH:15][CH3:16])[CH2:10][CH2:11][C:5]=2[CH:4]=1.[CH3:22][O:23][C:24]1[CH:25]=[C:26]([S:32][CH2:33][CH2:34][CH2:35]Cl)[CH:27]=[CH:28][C:29]=1[O:30][CH3:31]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[C:19]([O:20][CH3:21])=[CH:18][C:6]2[CH2:7][C:8](=[O:17])[N:9]([CH2:12][CH2:13][CH2:14][N:15]([CH3:16])[CH2:35][CH2:34][CH2:33][S:32][C:26]3[CH:27]=[CH:28][C:29]([O:30][CH3:31])=[C:24]([O:23][CH3:22])[CH:25]=3)[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

4

Reactant 2

HCID 100172197,8-Dimethoxy-3-[3-(methylamino)propyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 202401473-(3,4-Dimethoxyphenylthio)-propylchloride

Product 1

HCID 13579668HCID 13579668, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The title compound is prepared from N-[3-(7,8-dimethoxy-1,3,4,5- tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-methylamine and 3-(3,4-dimethoxyphenylthio)-propylchloride with the addition of pyridine analogously to Example 3.

Sources & evidence

ORD record
ord-415027b93e0c453593b58823bfb04e89
Source dataset
uspto-grants-1986_08
Patent number
US04604389

Reaction notes

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