HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-N-(3-phenylthiopropyl)-methylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-Chloropropyl phenyl sulfide | HCID 269606 | — |
| Reactant | 7,8-Dimethoxy-3-[3-(methylamino)propyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one | HCID 10017219 | — |
| Product | N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-N-(3-phenylthiopropyl)-methylamine | HCID 13579669 | — |
Reaction Steps
The title compound is prepared from N-[3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-methylamine and 3-phenylthiopropylchloride analogously to Example 3. M.p. of the hydrochloride: 130°-140° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04604389 |
| Source dataset | uspto-grants-1986_08 |
| ORD ID | ord-bf50155e211a4258ba84f758630ecc97 |
| Source note | uspto-grants-1986_08 |