Formaldehyde → HCID 20240082, compound

HRID 364083Notes

Reaction equation

HRID 364083 reaction equation
[CH3:1][O:2][C:3]1[C:28]([O:29][CH3:30])=[CH:27][C:6]2[CH2:7][C:8](=[O:26])[N:9]([CH2:12][CH2:13][CH2:14][NH:15][CH2:16][CH2:17][CH2:18][NH:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH2:10][CH2:11][C:5]=2[CH:4]=1.C=O.[C:33]([BH3-])#N.[Na+]>>[CH3:1][O:2][C:3]1[C:28]([O:29][CH3:30])=[CH:27][C:6]2[CH2:7][C:8](=[O:26])[N:9]([CH2:12][CH2:13][CH2:14][N:15]([CH3:33])[CH2:16][CH2:17][CH2:18][NH:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

4

Reactant 3

HCID 712FormaldehydeHCID 5003444Sodium cyanoborohydrideHCID 13579671HCID 13579671, compound

Product 1

HCID 20240082HCID 20240082, compound

Procedure

The title compound is prepared from N-[3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-3-phenylamino-propylamine, paraformaldehyde and sodium cyanoborohydride analogously to Example 5.

Sources & evidence

ORD record
ord-339dbb15c2374cf289b53dd096ea4f6e
Source dataset
uspto-grants-1986_08
Patent number
US04604389

Reaction notes

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