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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 3641Generated: October 29, 2026

Piperidine → 1,3-Di-cyclohexylmethyl-8-piperidinyl Xanthine

https://huagongshe.com/reaction/3641

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant1,3-Di-cyclohexylmethyl-8-bromo xanthineHCID 10202505—
Product1,3-Di-cyclohexylmethyl-8-piperidinyl XanthineHCID 10113349—

Reaction Steps

The title compound was prepared from 1,3-di-cyclohexylmethyl-8-bromo xanthine (0.7 g, 0.0017 mol) and piperidine (0.28 g, 0,003 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt. 266° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05734051
Source datasetuspto-grants-1998_03
ORD IDord-bc2d669ae91a4d3ca99ba757588a1739
Source noteuspto-grants-1998_03