Hydrogen Peroxide → HCID 20240077, compound

HRID 364101Notes

Reaction equation

[CH3:1][O:2][C:3]1[C:31]([O:32][CH3:33])=[CH:30][C:6]2[CH2:7][C:8](=[O:29])[N:9]([CH2:12][CH2:13][CH2:14][N:15]([CH3:28])[CH2:16][CH2:17][S:18][C:19]3[CH:24]=[C:23]([Br:25])[C:22]([NH2:26])=[C:21]([Br:27])[CH:20]=3)[CH2:10][CH2:11][C:5]=2[CH:4]=1.[OH:34]O>>[CH3:1][O:2][C:3]1[C:31]([O:32][CH3:33])=[CH:30][C:6]2[CH2:7][C:8](=[O:29])[N:9]([CH2:12][CH2:13][CH2:14][N:15]([CH3:28])[CH2:16][CH2:17][S:18]([C:19]3[CH:24]=[C:23]([Br:25])[C:22]([NH2:26])=[C:21]([Br:27])[CH:20]=3)=[O:34])[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

Reactant 2

HCID 784Hydrogen Peroxide

HCID 20240126HCID 20240126, compound

Product 1

HCID 20240077HCID 20240077, compound

Procedure

The title compound is prepared from N-[3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-N-[2-(4-amino-3,5-dibromophenylthio)-ethyl]-methylamine and 30% hydrogen peroxide (in glacial acetic acid) analogously to Example 4.

Sources & evidence

ORD record: ord-a661563b648441cabca1bcb6f4cde818
Source dataset: uspto-grants-1986_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04604389

Reaction notes

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