Selenium Dioxide → N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl]-N-[3-(3,4-dimethoxy-phenylsulfinyl)-propyl]-methylamine

HRID 364107Notes

Reaction equation

HRID 364107 reaction equation
[CH3:1][O:2][C:3]1[C:34]([O:35][CH3:36])=[CH:33][C:6]2[CH2:7][C:8](=[O:32])[N:9]([CH2:12][CH2:13][CH2:14][N:15]([CH3:31])[CH2:16][CH2:17][CH2:18][S:19]([C:21]3[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[C:23]([O:29][CH3:30])[CH:22]=3)=[O:20])[CH2:10][CH2:11][C:5]=2[CH:4]=1.[Se](=O)=[O:38]>>[CH3:1][O:2][C:3]1[C:34]([O:35][CH3:36])=[CH:33][C:6]2[C:7](=[O:38])[C:8](=[O:32])[N:9]([CH2:12][CH2:13][CH2:14][N:15]([CH3:31])[CH2:16][CH2:17][CH2:18][S:19]([C:21]3[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[C:23]([O:29][CH3:30])[CH:22]=3)=[O:20])[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 24007Selenium DioxideHCID 20240079N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-N-[3-(3,4-dimethoxyphenylsulfinyl)-propyl]-methylamine

Product 1

HCID 20240105N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl]-N-[3-(3,4-dimethoxy-phenylsulfinyl)-propyl]-methylamine

Procedure

The title compound is prepared from N-[3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-N-[3-(3,4-dimethoxy-phenylsulfinyl)-propyl]-methylamine and selenium dioxide analogously to Example 55.

Sources & evidence

ORD record
ord-802bbd4ea26f4b9b84437a691ad70568
Source dataset
uspto-grants-1986_08
Patent number
US04604389

Reaction notes

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