Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 364112Generated: October 30, 2026

3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-N-[2-(3,5-dichloro-4-methoxy-phenyloxy)-ethyl]-methylamine

https://huagongshe.com/reaction/364112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 13092510—
ReactantN-[2-(3,5-dichloro-4-methoxy-phenyloxy)-ethyl]-methylamineHCID 20240116—
SolventTriethylamineHCID 8471—
ProductN-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-propyl]-N-[2-(3,5-dichloro-4-methoxy-phenyloxy)-ethyl]-methylamineHCID 20240158—

Reaction Steps

The title compound is prepared from 3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-1-chloropropane, N-[2-(3,5-dichloro-4-methoxy-phenyloxy)-ethyl]-methylamine and triethylamine analogously to Example 6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04604389
Source datasetuspto-grants-1986_08
ORD IDord-6ff22932c2694fd3850630b5dd09641f
Source noteuspto-grants-1986_08