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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 364113Generated: October 29, 2026

3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl chloride → N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl]-N-[3-(4-amino-3,5-dibromophenyloxy)-propyl]-methylamine

https://huagongshe.com/reaction/364113

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl chlorideHCID 19847431—
ReactantN-[3-(4-amino-3,5-dibromophenyloxy)-propyl]-methylamineHCID 20240087—
SolventTriethylamineHCID 8471—
ProductN-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl]-N-[3-(4-amino-3,5-dibromophenyloxy)-propyl]-methylamineHCID 20240146—

Reaction Steps

The title compound is prepared from 3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-1-chloropropane, N-[3-(4-amino-3,5-dibromophenyloxy)-propyl]-methylamine and triethylamine analogously to Example 6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04604389
Source datasetuspto-grants-1986_08
ORD IDord-ea3c28581f89490e8301a4ab53bb78d1
Source noteuspto-grants-1986_08