Dicyclohexylamine → 3-[[(1-Hexenyl)carbonyl]ethoxyamino]pentanoic acid

HRID 364149Notes

Reaction equation

HRID 364149 reaction equation
[CH:1]([C:11]([OH:13])=O)=[CH:2][CH2:3][CH2:4][CH2:5][CH2:6]CCCC.Cl.[O:15]([NH2:18])[CH2:16][CH3:17].Cl.O(N)C.C([O:25][C:26](=[O:32])[CH2:27][CH:28](I)[CH2:29][CH3:30])C.C(OC(=O)CCCI)C.C1(NC2CCCCC2)CCCCC1>>[CH:1]([C:11]([CH2:17][CH2:16][O:15][NH:18][CH:28]([CH2:29][CH3:30])[CH2:27][C:26]([OH:32])=[O:25])=[O:13])=[CH:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

7

Reactant 6

HCID 7582DicyclohexylamineHCID 76850O-ethylhydroxylamine hydrochlorideHCID 519180Hendecenoic acidHCID 521874O-Methylhydroxylamine hydrochlorideHCID 10890062Ethyl 4-iodobutanoateHCID 20238940Ethyl-3 iodovalerate

Product 1

HCID 571471843-[[(1-Hexenyl)carbonyl]ethoxyamino]pentanoic acid

Procedure

Following the procedure of Example 12 except substituting 1-hexenylcarboxylic acid for 1-decenylcarboxylic acid, ethoxylamine hydrochloride for methoxylamine hydrochloride and ethyl-3 iodovalerate for ethyl-4-iodobutyrate, and eliminating the addition of dicyclohexylamine, the title compound is obtained.

Sources & evidence

ORD record
ord-2ee3a863b6fc47f3a1ce4ae7e475a4e3
Source dataset
uspto-grants-1986_08
Patent number
US04604407

Reaction notes

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