Cyclohexylamine → HCID 178440548, compound

HRID 364153Notes

Reaction equation

[CH2:1]([CH2:4][C:5]12[CH2:11][CH:8]([CH:9]=[CH:10]1)[CH:7]1[C:12]([O:14][C:15](=[O:16])[CH:6]21)=[O:13])[CH:2]=[CH2:3].[CH:17]1([NH2:23])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1>>[CH:17]1([N:23]=[C:15]([CH:6]2[CH:7]([C:12]([OH:14])=[O:13])[CH:8]3[CH2:11][C:5]2([CH2:4][CH2:1][CH:2]=[CH2:3])[CH:10]=[CH:9]3)[OH:16])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1

Participants

Reactant 2

HCID 7965Cyclohexylamine

HCID 53956536HCID 53956536, compound

Product 1

HCID 178440548HCID 178440548, compoundYield 58.2%

Conditions

Temperature: 135 °C

Procedure

A mixture of 20 g of allylmethylbicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride and 9.09 g of cyclohexylamine is heated at 135° C. for 3 hours, and the product is then distilled in vacuo. 16 g of a yellow, viscous oil distill over between 128° and 138° C. at 2.5 Pa, corresponding to a yield of 58.2%.

Workup

distillationthe product is then distilled in vacuo
distillation16 g of a yellow, viscous oil distill over between 128° and 138° C. at 2.5 Pa, corresponding to a yield of 58.2%

Sources & evidence

ORD record: ord-efa4c0726d064f5f9cfcab91a3c2bed8
Source dataset: uspto-grants-1986_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04604437

Reaction notes

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