HCID 13689010, compound → HCID 20240228, compound

HRID 364166Notes

Reaction equation

HRID 364166 reaction equation
[CH2:1]([N:3]([CH2:27][CH3:28])[CH2:4][CH2:5][N:6]1[C:14]2[CH:13]=[CH:12][C:11]([N+:15]([O-])=O)=[C:10]3[O:18][C:19]4[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][C:20]=4[C:8]([C:9]=23)=[N:7]1)[CH3:2]>[Pd].O1CCCC1>[NH2:15][C:11]1[CH:12]=[CH:13][C:14]2[N:6]([CH2:5][CH2:4][N:3]([CH2:1][CH3:2])[CH2:27][CH3:28])[N:7]=[C:8]3[C:20]4[CH:21]=[C:22]([O:25][CH3:26])[CH:23]=[CH:24][C:19]=4[O:18][C:10]=1[C:9]=23

Participants

4

Reactant 1

HCID 13689010HCID 13689010, compound

Product 1

HCID 20240228HCID 20240228, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 5 g of N,N-diethyl-9-methoxy-5-nitro-2H-[1]-benzopyrano[4,3,2-cd]indazole-2-ethanamine, and 0.940 g of 10% palladium on carbon, in 250 ml of tetrahydrofuran was stirred under hydrogen atmosphere for 18 hours, filtered, and the filtrate concentrated to give 5-amino-N,N-diethyl-9-methoxy-2H-[1]benzopyrano[4,3,2-cd]indazole-2-ethanamine.

Workup

  1. filtrationfiltered
  2. concentrationthe filtrate concentrated

Sources & evidence

ORD record
ord-f406eacf6ff948ed832d10fe5d17c178
Source dataset
uspto-grants-1986_08
Patent number
US04604390

Reaction notes

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