HCID 13689097, compound → HCID 13689090, compound

HRID 364180Notes

Reaction equation

HRID 364180 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:21]([O-:23])=[O:22])=[C:6]([CH:20]=1)[O:7][C:8]1[CH:17]=[C:16]([O:18][CH3:19])[CH:15]=[CH:14][C:9]=1[C:10]([O:12]C)=O>O>[Cl:1][C:2]1[C:20]2[C:10](=[O:12])[C:9]3[C:8](=[CH:17][C:16]([O:18][CH3:19])=[CH:15][CH:14]=3)[O:7][C:6]=2[C:5]([N+:21]([O-:23])=[O:22])=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 13689097HCID 13689097, compound

Product 1

HCID 13689090HCID 13689090, compoundYield 101.7%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 500 g of polyphosphoric acid stirred at 110° C. was added 62.9 g of 2-(5-chloro-2-nitrophenoxy)-4-methoxybenzoic acid, methyl ester. After 18 hours, the hot solution was poured into water, and the resulting precipitate collected. The solid was washed with water and isopropyl alcohol to give 57.9 g of the title compound, mp 211°-213° C. after recrystallization from DMF.

Workup

  1. customthe resulting precipitate collected
  2. washThe solid was washed with water and isopropyl alcohol

Sources & evidence

ORD record
ord-3be4be88cf584811b29bc2f52f4ec7c4
Source dataset
uspto-grants-1986_08
Patent number
US04604390

Reaction notes

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