HCID 13689097, compound → HCID 13689090, compound

Participants

Reaction Steps

To 500 g of polyphosphoric acid stirred at 110° C. was added 62.9 g of 2-(5-chloro-2-nitrophenoxy)-4-methoxybenzoic acid, methyl ester. After 18 hours, the hot solution was poured into water, and the resulting precipitate collected. The solid was washed with water and isopropyl alcohol to give 57.9 g of the title compound, mp 211°-213° C. after recrystallization from DMF.

Provenance & Evidence