Sodium methanethiolate → HCID 13377373, compound

HRID 364240Notes

Reaction equation

HRID 364240 reaction equation
Cl[C:2]1[N:7]2[C:8]([CH3:11])=[N:9][CH:10]=[C:6]2[CH:5]=[C:4]([Cl:12])[N:3]=1.[CH3:13][S-:14].[Na+]>>[Cl:12][C:4]1[N:3]=[C:2]([S:14][CH3:13])[N:7]2[C:8]([CH3:11])=[N:9][CH:10]=[C:6]2[CH:5]=1

Participants

3

Reactant 2

HCID 4378561Sodium methanethiolateHCID 133773425,7-Dichloro-3-methylimidazo[1,5-c]pyrimidine

Product 1

HCID 13377373HCID 13377373, compound

Procedure

Using the method of Example 53, 5,7-dichloro-3-methylimidazo[1,5-c]pyrimidine (from Example 35) was reacted with sodium methanethiolate to provide yellow solid 7-chloro-3-methyl-5-methylthioimidazo[1,5-c]pyrimidine, m.p. 153°-155° C. Analysis: Calculated for C8H8ClN3S: %C, 45.0; %H, 3.8; %N, 19.7; Found: %C, 44.8; %H, 3.5; %N, 19.7.

Sources & evidence

ORD record
ord-1a6e60385c9a4181bc5ecd34bba8bfd9
Source dataset
uspto-grants-1986_08
Patent number
US04604466

Reaction notes

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