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HRID364518

反应详情

EQUATION

反应方程式

HRID 364518 的结构方程式

REACTANTS

反应物

2
结构：[Mg+2].[OH-].[OH-]
HCID73981

未命名化合物

结构：CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CCS[C@H]12)c1csc(N)n1
HCID131712444

未命名化合物

PRODUCTS

生成物

1
结构：CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=CCS[C@H]12)c1csc(N)n1.CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=CCS[C@H]12)c1csc(N)n1.[Mg+2]
HCID131712447

未命名化合物

收率 93%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

CONDITIONS

反应条件

温度
70 °C

PROCEDURE

实验过程

7-[2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid (syn isomer, 1.15 g.) was added to a suspension of magnesium hydroxide (0.088 g.) in water (100 ml.), and the mixture was stirred at 70° C. for 30 minutes to give a solution. After the resultant solution was filtered, the filtrate was lyophilized to give magnesium 7-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylate (syn isomer, 1.1 g.).

WORKUP

后处理

  1. customto give a solution
  2. filtrationAfter the resultant solution was filtered