Tertiary-butyl(iso-butyl)(diethoxymethyl)phosphine oxide → HCID 178454902, compound

HRID 36457Notes

Reaction equation

HRID 36457 reaction equation
[C:1]([P:5](=[O:17])([CH2:13][CH:14]([CH3:16])[CH3:15])C(OCC)OCC)([CH3:4])([CH3:3])[CH3:2]>Cl>[C:1]([PH:5](=[O:17])[CH2:13][CH:14]([CH3:16])[CH3:15])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 19938716Tertiary-butyl(iso-butyl)(diethoxymethyl)phosphine oxide

Product 1

HCID 178454902HCID 178454902, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of 1.2 g (0.005 mol) of tertiary-butyl(iso-butyl)(diethoxymethyl)phosphine oxide in 10 ml of 5% hydrochloric acid is heated at 80° C. for 9 hours. After this the mixture is allowed to cool to room temperature, evaporated under reduced pressure and the crude product is extracted into chloroform and washed with water. The organic extract is dried and evaporated to give tertiary-butyl(iso-butyl)phosphine oxide as a pale yellow oil.

Workup

  1. customevaporated under reduced pressure
  2. extractionthe crude product is extracted into chloroform
  3. washwashed with water
  4. extractionThe organic extract
  5. customis dried
  6. customevaporated

Sources & evidence

ORD record
ord-888d53d53a3d41ac82bc6495fa138cb7
Source dataset
uspto-grants-1995_05
Patent number
US05414133

Reaction notes

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