1,1'-Carbonyldiimidazole → HCID 19851506, compound

HRID 364641Notes

Reaction equation

HRID 364641 reaction equation
[CH3:1][N:2]([CH3:14])[C:3]1[N:8]=[C:7]([O:9][CH3:10])[C:6]([C:11]([OH:13])=O)=[CH:5][N:4]=1.C(N1C=CN=C1)(N1C=CN=C1)=O.[NH2:27][CH:28]1[CH:33]2[CH2:34][CH2:35][N:30]([CH2:31][CH2:32]2)[CH2:29]1>>[N:30]12[CH2:35][CH2:34][CH:33]([CH2:32][CH2:31]1)[CH:28]([NH:27][C:11]([C:6]1[C:7]([O:9][CH3:10])=[N:8][C:3]([N:2]([CH3:1])[CH3:14])=[N:4][CH:5]=1)=[O:13])[CH2:29]2

Participants

4

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 1232383-AminoquinuclidineHCID 12828960HCID 12828960, compound

Product 1

HCID 19851506HCID 19851506, compound

Procedure

Following the procedure of Example 22, 2-(dimethylamino)-4-methoxy-5-pyrimidinecarboxylic acid, 1,1'-carbonyldiimidazole and 3-aminoquinuclidine are reacted to give the title compound.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-72e96a78485146abbaf109ed16bfb59f
Source dataset
uspto-grants-1986_08
Patent number
US04605652

Reaction notes

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