1,1'-Carbonyldiimidazole → HCID 13272325, compound

HRID 364643Notes

Reaction equation

HRID 364643 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([O:8][CH3:9])[C:5]([C:10]([OH:12])=O)=[CH:4][N:3]=1.C(N1C=CN=C1)(N1C=CN=C1)=O.[NH2:25][CH:26]1[CH:31]2[CH2:32][CH2:33][N:28]([CH2:29][CH2:30]2)[CH2:27]1>>[NH2:1][C:2]1[N:7]=[C:6]([O:8][CH3:9])[C:5]([C:10]([NH:25][CH:26]2[CH:31]3[CH2:32][CH2:33][N:28]([CH2:29][CH2:30]3)[CH2:27]2)=[O:12])=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 1232383-AminoquinuclidineHCID 128289592-Amino-4-methoxypyrimidine-5-carboxylic acid

Product 1

HCID 13272325HCID 13272325, compound

Procedure

Following the procedure of Example 22, 2-amino-4-methoxy-5-pyrimidinecarboxylic acid, 1,1'-carbonyldiimidazole and 3-aminoquinuclidine are reacted to give the title compound.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-118b780d08b84550811a43d793dfb227
Source dataset
uspto-grants-1986_08
Patent number
US04605652

Reaction notes

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