Triethanolamine → HCID 178484944, compound

HRID 364865Notes

Reaction equation

HRID 364865 reaction equation
Cl.CN.[N:4](CCO)(CCO)[CH2:5]CO.[C:14]([CH2:17][N:18]1[C:22](=[O:23])[C:21](=[CH:24]OCC)[S:20][C:19]1=[S:28])([OH:16])=[O:15]>C(O)C>[CH3:5][NH2:4].[C:14]([CH2:17][N:18]1[C:22](=[O:23])[C:21](=[CH:24][NH:4][CH3:5])[S:20][C:19]1=[S:28])([OH:16])=[O:15]

Participants

5

Reactant 3

HCID 7618TriethanolamineHCID 6364545Methylamine hydrochlorideHCID 54431541HCID 54431541, compound

Product 1

HCID 178484944HCID 178484944, compoundYield 79.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A mixture of 0.68 g (0.010 mole) of methylamine hydrochloride and 5 ml of ethanol, which was neutralized with 1.0 g (0.010 mole) of triethanolamine, was added to a mixture of 1.2 g (0.005 mole) of 3-carboxymethyl-5ethoxymethylidenerhodanine and 10 ml of ethanol. The reaction was conducted at a temperature of 50° to 60° C. for 1 hour. The reaction mixture was concentrated and the resulting residue was recrystallized from ethanol to give 1.0 g of 3-carboxymethyl-5-methylaminomethylidenerhodanine methylamine salt (yield: 79.2 %).

Workup

  1. concentrationThe reaction mixture was concentrated
  2. customthe resulting residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-f554fae2117845d8b92c170acb3ca7e2
Source dataset
uspto-grants-1986_08
Patent number
US04606860

Reaction notes

Loading…