Allylamine → HCID 178457126, compound

HRID 364867Notes

Reaction equation

HRID 364867 reaction equation
[CH2:1]([NH2:4])[CH:2]=[CH2:3].[C:5]([CH2:8][N:9]1[C:13](=[O:14])[C:12](=[CH:15]OCC)[S:11][C:10]1=[S:19])([OH:7])=[O:6]>C(O)C>[C:5]([CH2:8][N:9]1[C:13](=[O:14])[C:12](=[CH:15][NH:4][CH2:1][CH:2]=[CH2:3])[S:11][C:10]1=[S:19])([OH:7])=[O:6]

Participants

4

Reactant 2

HCID 7853AllylamineHCID 54431541HCID 54431541, compound

Product 1

HCID 178457126HCID 178457126, compoundYield 52.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

0.3 Gram (0.005 mole) of allylamine was added to a mixture of 1.2 g (0.005 mole) of 3-carboxymethyl-5-ethoxymethylidenerhodanine and 10 ml of ethanol, and the resulting mixture was subjected to reaction at a temperature of 50° to 60° C. for 1 hour. The reaction mixture was cooled and the formed precipitate was separated by filtration and recrystalized from a mixture of methanol and ether (7/3 by volume) to give 0.68 g of 3-carboxymethyl-5-allylaminomethylidenerhodanine in the form of yellow crystal (yield: 52.6%).

Workup

  1. customthe resulting mixture was subjected to reaction at a temperature of 50° to 60° C. for 1 hour
  2. temperatureThe reaction mixture was cooled
  3. customthe formed precipitate was separated by filtration
  4. customrecrystalized from a mixture of methanol and ether (7/3 by volume)

Sources & evidence

ORD record
ord-5a3973f93ca94ebca11477b100131060
Source dataset
uspto-grants-1986_08
Patent number
US04606860

Reaction notes

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