HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 13714123, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Chloro-6,7-dimethoxy-4-quinazolinamine | HCID 90235 | — |
| Reactant | HCID 16770658 | HCID 16770658 | — |
| Solvent | Isoamyl Alcohol | HCID 31260 | — |
| Product | HCID 13714123 | HCID 13714123 | — |
Reaction Steps
A solution prepared by dissolving 479 mg. (2 mmole) of 2-chloro-4-amino-6,7-dimethoxyquinazoline and 451 mg. (2 mmole) of N-cyclohexylcarbamoyl-homopiperazine (oily substance, showing IR absorption spectrum at 3340, 2920, 1630 cm-1) in 10 ml of isoamyl alcohol was refluxed for 4 hours, followed by standing overnight. The precipitates were collected by filtration to obtain 310 mg. of the desired hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04607034 |
| Source dataset | uspto-grants-1986_08 |
| ORD ID | ord-94df663e08e84aba94f6cb2b9c0f5f48 |
| Source note | uspto-grants-1986_08 |