HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide → 2-Aminomethyl-4-(1,1-dimethylethyl)-6-sulfamoylphenol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide | HCID 53948117 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Aminomethyl-4-(1,1-dimethylethyl)-6-sulfamoylphenol hydrochloride | HCID 21296905 | — |
Reaction Steps
3 g (0.008 mole) of 2-chloro-N-[5-(1,1-dimethylethyl)-3 -dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide in a mixture of 30 ml of ethanol and 3 ml of concentrated hydrochloric acid are heated under reflux for 2 hours. The solvent is removed in vacuo and the residue is crystallized from methanol/ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04607030 |
| Source dataset | uspto-grants-1986_08 |
| ORD ID | ord-099715e9b0204e519f67ab46d01adaef |
| Source note | uspto-grants-1986_08 |