Acetone → HCID 70455662, compound

HRID 364932Notes

Reaction equation

HRID 364932 reaction equation
CC(C)=[O:3].[ClH:5].[NH:6]1[CH:10]=[CH:9][N:8]=[C:7]1[CH2:11][C:12]1[CH:22]=[CH:21][C:15]([CH:16]=[CH:17][C:18]([OH:20])=[O:19])=[CH:14][CH:13]=1>O>[OH2:3].[ClH:5].[NH:6]1[CH:10]=[CH:9][N:8]=[C:7]1[CH2:11][C:12]1[CH:22]=[CH:21][C:15]([CH:16]=[CH:17][C:18]([OH:20])=[O:19])=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 180AcetoneHCID 70040791HCID 70040791, compound

Product 1

HCID 70455662HCID 70455662, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In 60 ml of aqueous solution of acetone having water content of 25% (V/V%), 10 g of 4-(1-imidazolylmethyl)cinnamic acid hydrochloride was dissolved by heating and then the solution was allowed to stand overnight at room temperature. The resulting precipitates were collected by filtration and dried at room temperature for 3 hr under reduced pressure to obtain 7.0 g of 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate. This product had the same IR-absorption spectrum and NMR spectrum as those of the product of EXAMPLE 1.

Workup

  1. dissolutionwas dissolved
  2. temperatureby heating
  3. customThe resulting precipitates
  4. filtrationwere collected by filtration
  5. customdried at room temperature for 3 hr under reduced pressure

Sources & evidence

ORD record
ord-6575d1f85116418c8f98ad8664b435c7
Source dataset
uspto-grants-1986_08
Patent number
US04607046

Reaction notes

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