反应详情

4-Picoline (2.79 g, 0.03 mole) and 1-bromohexane (4.25 ml, 0.03 mole) were heated in an oil bath at 130° C. for 2 hours. The resulting brown oil was cooled. Methanol (40 ml), 4-dimethylaminobenzaldehyde (4.5 g, 0.03 mole) and piperdine (0.25 ml) were added. The mixture was refluxed for 3 hours and cooled. A large volume of ether was added to form a crystalline product which was recrystallised by dissolving in isopropyl alcohol and adding ether to give crystals of 4-[4-(dimethylamino)styryl]-1-hexylpyridinium bromide quarter hydrate (2.2 g), melting point 224°-226° C. (decomposition). The compound exhibited infra-red spectral bands at 720, 815, 835, 883, 940, 987, 1158, 1330, 1362, 1522, 1575 and 1640 wavenumbers.

1. temperatureThe resulting brown oil was cooled
2. temperatureThe mixture was refluxed for 3 hours
3. temperaturecooled
4. customto form a crystalline product which
5. customwas recrystallised
6. dissolutionby dissolving in isopropyl alcohol
7. additionadding ether