((p-(Benzyloxy)phenoxy)methyl)oxirane → HCID 20237814, compound

HRID 365189Notes

Reaction equation

HRID 365189 reaction equation
[CH2:1]([O:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)[CH:2]1[O:4][CH2:3]1.[CH3:20][C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([CH3:27])[C:22]=1[NH:28][CH2:29][CH2:30][CH2:31][NH2:32]>C(O)(C)C>[CH2:13]([O:12][C:9]1[CH:10]=[CH:11][C:6]([O:5][CH2:1][CH:2]([OH:4])[CH2:3][NH:32][CH2:31][CH2:30][CH2:29][NH:28][C:22]2[C:23]([CH3:27])=[CH:24][CH:25]=[CH:26][C:21]=2[CH3:20])=[CH:7][CH:8]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 119882((p-(Benzyloxy)phenoxy)methyl)oxiraneHCID 15572226HCID 15572226, compound

Product 1

HCID 20237814HCID 20237814, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

4.23 g. 4-Benzyloxyphenyl glycidyl ether, 5.9 g. N-(2,6-dimethylphenyl)-1,3-diaminopropane and 5 ml. isopropyl alcohol are stirred for 24 hours at ambient temperature. The reaction mixture is worked up by chromatography on silica gel.

Sources & evidence

ORD record
ord-caf80afee011470082e4eb688dbf433c
Source dataset
uspto-grants-1986_08
Patent number
US04608383

Reaction notes

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