Phenyl glycidyl ether → HCID 20237785, compound

Participants

Reaction Steps

3.32 g. Phenyl glycidyl ether and 9.0 g. 2-amino-4-(2-aminoethylamino)-quinazoline are stirred for 24 hours at 50° C. in 100 ml. isopropyl alcohol. The reaction mixture is then evaporated and the residue purified chromatographically in the manner described in Example 38. There are obtained 2.0 g. (26% of theory) of the desired product in the form of a colorless oil.

Provenance & Evidence