反应详情

Ammonium formate (3.40 g, 0.054 mol) and 10% palladium on charcoal (1.44 g) were added to a stirred solution of the product of example 12 (2.45 g, 0.0135 mol) in methanol (15 ml). After the considerable effervescence had ceased, the mixture was filtered, evaporated in vacuo and triturated with acetonitrile. The residue was purified by chromatography (silica; ether) to give the product (1.51 g).

1. filtrationthe mixture was filtered
2. customevaporated in vacuo
3. customtriturated with acetonitrile
4. customThe residue was purified by chromatography (silica; ether)