HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetic Acid → HCID 178515561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178515562 | HCID 178515562 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178515561 | HCID 178515561 | 83.5% |
Reaction Steps
2-Mercapto-4-hydroxy-6-phenylpyrimidine (8.6 g, 42 mmol) and chloroacetic acid (8.5 g, 90 mmol) were slurried in water (100 mL). After refluxing the mixture for 24 hours, hydrochloric acid was added and the precipitate was isolated by filtration. The solid was dried in a vacuum oven to give 6.6 g (83%) of 2,4-dihydroxy-6-phenylpyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06127376 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-a3cc2acde48c4247bf242b2e0329e535 |
| Source note | uspto-grants-2000_10 |