ethyl 2-(3,4-dihydronaphthalen-2-yl)acetate → HCID 54427283, compound

HRID 365495Notes

Reaction equation

HRID 365495 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][C:2]=1[CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13]>CCO.[Pd]>[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13]

Participants

4

Reactant 1

HCID 313346ethyl 2-(3,4-dihydronaphthalen-2-yl)acetate

Product 1

HCID 54427283HCID 54427283, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of 26 g (0.12 mol) of the ester obtained in Step 1 of Example 1 and 2.50 g of Pd/C 10% in 250 ml of EtOH is hydrogenated under 1 bar, at 20° C., overnight. After filtering off the catalyst and washing with ethanol, the filtrate is concentrated in vacuo to yield the expected compound in the form of a colourless oil.

Workup

  1. filtrationAfter filtering off the catalyst
  2. washwashing with ethanol
  3. concentrationthe filtrate is concentrated in vacuo

Sources & evidence

ORD record
ord-f9b2ef75661b47c2b4ee8f1a9877b9d0
Source dataset
uspto-grants-2000_10
Patent number
US06127396

Reaction notes

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