N-(3-Aminopropyl)morpholine → HCID 23293027, compound
Reaction equation
F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[NH2:10][CH2:11][CH2:12][CH2:13][N:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>>[O:17]1[CH2:18][CH2:19][N:14]([CH2:13][CH2:12][CH2:11][NH:10][C:2]2[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=2[C:4]#[N:5])[CH2:15][CH2:16]1Participants
3
Procedure
According to a similar manner to that in Reference Example 3, the title compound was synthesized from 2-fluorobenzonitrile and 4-(3-aminopropyl)morpholine.
Sources & evidence
- ORD record
- ord-3159ff0ddd254801a9afabe6222e8c25
- Source dataset
- uspto-grants-2000_10
- Patent number
- US06127541
Reaction notes
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