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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 365725Generated: October 31, 2026

2-Fluorobenzonitrile → ethyl 1-(2-cyanophenyl)-4-piperidinecarboxylate

https://huagongshe.com/reaction/365725

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorobenzonitrileHCID 67855—
ReactantEthyl 4-piperidinecarboxylateHCID 70770—
Productethyl 1-(2-cyanophenyl)-4-piperidinecarboxylateHCID 2764422—

Reaction Steps

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and ethyl isonipecotate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06127541
Source datasetuspto-grants-2000_10
ORD IDord-1d02251f5a9e466f957e530bb017dd38
Source noteuspto-grants-2000_10